Question 1

How does Xeomin work?

Accepted Answer

When you squint or frown, the muscles between your eyebrows contract, causing the skin to furrow and fold. Over time, as your skin ages and loses some of its elasticity, these repeated contractions can cause persistent frown lines. Botulinum toxin type A – the active ingredient in Xeomin– acts on nerve endings in muscles to prevent muscle fibers from contracting. By reducing these contractions, Xeomin can temporarily reduce the lines between your eyebrows.

Question 2

Is Xeomin proven?

Accepted Answer

Xeomin was proven effective in two randomized, double-blind, multicenter, placebo-controlled clinical trials of 547 healthy, adult patients. The average age of patients in the study was 46 years. Patients received 20 Units of Xeomin and were classified as responders if they had a 2-grade improvement on a 4-point scale as assessed by the physician and patient. Using these criteria, treatment success was higher with Xeomin than placebo on Day 30 in both studies (60% and 48% vs. 0% for placebo in both studies). Based on these trials, Xeomin received FDA approval for use in glabellar lines in 2011.

Question 3

What can I expect during treatment?

Accepted Answer

During treatment, which usually takes about 10-20 minutes, Dr. Nolten will inject Xeomin into the muscles in your forehead that cause frown lines between your eyebrows. No anesthesia is required; however, Dr. Nolten may use a topical anesthetic or cold pack to reduce any discomfort.

Question 4

How do I know if Xeomin is right for me?

Accepted Answer

If you are an adult with moderate to severe glabellar lines, Xeomin may be right for you. Talk to Dr. Nolten to discuss the benefits and risks of treatment. Do not use Xeomin if you are allergic to botulinum toxin or any of the other ingredients in Xeomin. You should also not use Xeomin if you have had an allergic reaction to any other botulinum toxin product or have a skin infection at the planned injection site.

Question 5

When can I expect to see the results?

Accepted Answer

You may begin to see visible smoothing as early as 3-4 days after injection. The median first onset of effect was less than a week. The maximum effect occurred at 30 days. The typical duration of effect was up to 3 months in clinical trials but may last significantly longer or shorter in individual patients.

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